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KNC Laboratories Co., Ltd.
【Field/Business】
Pharmaceutical/Drug Discovery
Drug discovery support/Contract service
Chemical/Cosmetic/Fiber
last update:2022/8/24
Profile

Delegates :
President Hitoshi Miyauchi


Incorporated :
January  22 , 1985

Paid in Capital :
1995 Million yen  

Employees :
295 members

Address :
7-1-19, Minatojimaminamimachi, Chuo-ku, Kobe, Japan HYOGO
〒650-0047

TEL/FAX :
+81-78-955-9900 / +81-78-955-9901

URL:
http://www.kncweb.co.jp/en/index.html

Attachment :

Mission/Background :
KNC Laboratories provides R&D and manufacturing services promptly and flexibly in any phase of your activity, from early research to commercial production. KNC Laboratories has been serving many industries including pharmaceutical, electronics chemical, agrochemical, energy, and environment. With expertise in organic chemistry and biochemistry, KNC Laboratories offers services such as OEM, R&D manufacturing, FTE to meet customer's requirement in any phase of business.

Technology & Business
We hope that our clients take full advantage of our skills in chemistry accumulated in synthesizing more than 900 compounds a year, and also skills in pilot scale production and full scale production. We also have teams specializing in the areas of carbohydrate, steroid, nucleoside, peptide, oligonucleotide, microbial fermentation, extraction and purification, combinatorial chemistry medicinal chemistry, and also process research & development chemistry. Especially in our microbial fermentation services, we offer client's target proteins, secondary metabolites, and bioconverted compounds in mg to kg order using our separation and purification technology. It is possible to scale up to 5,000 L under GMP regulations. Working area for genetic technology, from culture to removal of microorganism, is controlled under P1 level, as well as GILSP.
Products & Service
Products & Service Name
Stage
Outline
Milestone
Microbial culture (GMP)
Service/Marketing
Cultivation services of a various kinds of microorganisms including genetically modified strains are offered.
Our facility is equipped with 200 L and 500 L fermenter tanks controlled under GMP. We'll also offer a master cell bank service.
Middle molecule drugs (peptide, oligonucleotide)
Service/Marketing
For the production of large amount of oligo DNA, we developed a new liquid synthesis method with an original polymer support.
We'll start to supply 1 kg of product per 1 batch (GMP).
Bioconversion
Service/Marketing
We provide customers with optically active organic compounds by a bioconversion system with the chiral screening technology.
The synergy effect of our fundamental organic synthesis technology and biotechnology will be committed to customer's requests.
Organic synthesis of small molecule drugs (GMP)
Service/Marketing
We address everything from drug discovery to production of drug substances and pharmaceutical intermediates.
We aim to increase orders for new products based on an efficient and stable production.
Process development
Service/Marketing
We will further strengthen the commissioned services in the developmental stage of pharmaceutical manufacturing process.
We'll develop R&D system for pharmaceuticals to bolster the support work related to Chemistry, Manufacturing and Control (CMC).
Highlights
A developmental research not only based on commissioned business, but also bearing the cost in-house is conducted to construct a high profitable business by a joint application of patent, etc. We especially focus on the medium molecule drugs business. In the mass production of oligonucleotide therapeutics, we developed a new liquid phase synthesis method using a batch type solid phase synthesizer with an original polymer support.
Hot news
In Dec. 2019, our head office and research facility were moved to Port Island in Kobe and expanded. Furthermore in May 2020, a new facility for purification of drug substances has been introduced at the Izumo plant.
Alliance strategy
Sales in pharmaceutical field account for a half of total revenue of KNC Laboratories. We provide R&D and manufacturing services promptly and flexibly in any phase of your activity, from early research to commercial production. We also offer pharmaceutical intermediates for low molecule drug, investigational new drugs, and drug substances under control of GMP. It is possible to produce medium molecule drugs (peptide, oligo nucleotide) and biopharmaceutical drug substances, too.

 
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